Immunology

The evaluation of lymphocyte subpopulations or immunophenotype by flow cytometry is the most complete study to assess the status of the immune system.

Lymphocyte typing has become an indispensable tool in recent years for the diagnosis and monitoring of immunological, infectious, autoimmune, and oncological diseases. It consists of the detection, characterization, and quantification of the various lymphocyte populations according to their biological function through flow cytometry.

At Teletest, we have the most advanced technology in flow cytometry for the detection of each specific cell type. We have an extensive catalog of tests for the detailed study of the functioning of the immune system.

IMMUNE STATUS

BASIC: Evaluation of the immune system and study of viral infections/reactivations or latent viruses.

EXTENDED: Includes the inflammatory response.

PLUS: Includes the study of effector T cells and cytokine production.

• Leuko Status (ILMI): [LEU], [LINF], T Lymphocytes, [T4], [T8], [T4/T8], [Tact], [T4act], [T8act], [T4H], [TN], [T4h/T4n], [Treg], [T8 cito], [T8senescentes], [T8c/T8s], [NK], [B], [Bact], Soluble Interleukin 2 Receptor, neutrophils, basophils, and eosinophils. Includes Interpretation.
• Viral Status: Available Basic profile (evaluates the humoral response) and Extended (evaluates the humoral response and active infections (IgG and IgM)) Epstein Barr EBV, Cytomegalovirus CMV, Varicella Zoster VZV, Herpes Virus HSV type I and type 2, Parvovirus B19.
• Protein Status: Inflammatory response. Albumin, Prealbumin, Transferrin, Ultrasensitive C-reactive protein, IgA, IgG, IgM, IgE, Haptoglobin, alpha 1-acid glycoprotein (Orosomucoid), C3, C4

• Cytokin Status (IL Status): Determines pro-inflammatory and anti-inflammatory cytokines to evaluate the suitability of a treatment and the status of the immune system. GM-CSF, IFNa, IFNg, IL2, IL4, IL5, IL6, IL9, IL10, IL12p70, IL17A, TNFa
• TH Status + Tregs: TH1, TH2, TH17, TH19, TH22, Regulators, TH1/TH2 ratio, TH17/Tregs ratio, TH17;TH1 population

CELLULAR STATUS · CELLULAR RESPONSE

The Cellular Status studies the cellular and humoral immunological response against the studied virus, to assess whether the pathogen is in acute/latent/reactivated infection, through the production of IFNgamma. Depending on the pathogen under study, cell typing and the humoral response are designed.

• COVID: The immunological memory / cellular response to COVID is evaluated by vaccination, by natural infection with the virus, or if there is innate immunity to respond against the virus. A lymphocyte typing, serology of SARS-COV2 (IgG (S1) IgG (N), IgM) is included
• CMV by ELISPOT: Cytomegalovirus (CMV) serology, avidity evaluation to indicate whether it is a recent or old infection, Lymphocyte typing, cellular response and conclusion on a possible viral reactivation.
• EBV by ELISPOT: Epstein Barr serology, Lymphocyte Typing, CD57 Expression in NK, cellular response and conclusion on a possible viral reactivation and the degree of immunity against the virus.
• Borrelia: assessment of Lyme Disease against Borrelia afzelii, B garinii, B burgdorferi. A lymphocyte typing, Borrelia IgG and IgM serology by immunoblot is included.

Contact the laboratory for more information on sample conditions