Difference between SIBO, intolerances, food sensitivity, and allergies

Difference between SIBO, intolerances, food sensitivity, and allergies

 

Laboratorio de Análisis en Barcelona, Madrid y Málaga - Análisis Clínicos | Difference between SIBO, intolerances, food sensitivity, and allergies

Not everything that upsets you has the same cause: intolerances, sensitivities, allergies, or SIBO. How can you tell them apart?

Symptoms such as bloating, gas, diarrhea, abdominal pain, or discomfort after eating can be due to different causes and involve different biological mechanisms, and they are not all investigated in the same way.

From an analytical standpoint, not all of these conditions are studied with the same tests, so distinguishing them correctly is key to guiding the evaluation and avoiding misinterpretations.

 

What could be behind your symptoms?

✔️SIBO: when the issue is intestinal fermentation

→ It is characterized by abnormal bacterial fermentation in the small intestine, where this activity is normally limited.

→ It may present with abdominal bloating, excess gas, abdominal pain, and changes in bowel habits.

→ It is assessed by measuring gases (hydrogen and methane) with the Breath Test after administering glucose or lactulose, which allows fermentation patterns to be evaluated.

 

✔️Intolerances: when a sugar isn’t digested or absorbed properly

→ Related to incomplete digestion or malabsorption of certain carbohydrates such as lactose, fructose, or sorbitol.

There may also be other forms of genetically based intolerance or intolerance related to other food components, such as gluten. In these cases, the diagnostic approach and type of study may differ, so it’s important not to confuse them with carbohydrate intolerances assessed using the Breath Test.

→ They usually cause digestive symptoms after consuming the sugar involved, such as gas, bloating, diarrhea, or abdominal discomfort.

→ They are assessed with a specific Breath Test depending on the substrate administered, analyzing hydrogen and methane production after it is metabolized.

 

✔️Food sensitivity: an immune response not mediated by IgE

→ possible immune response to certain foods

→ digestive discomfort or other symptoms that don’t fit a specific intolerance or a typical allergic reaction.

→ assessed by measuring IgG/IgG4

 

✔️Allergy: not the same as intolerance

→ different immune mechanism: an IgE-mediated allergic reaction

→ It can cause symptoms such as itching, hives, swelling, and breathing difficulty.

→ assessment of molecular allergy/specific IgE with the ALEX³ Test

 

Laboratorio de Análisis en Barcelona, Madrid y Málaga - Análisis Clínicos | Difference between SIBO, intolerances, food sensitivity, and allergies

 

If any of these symptoms sound familiar, the best course of action is to consult a healthcare professional to determine which test may be the best fit for your case.

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