Neuro. Alzheimer. Extended Profile

442,14 

p-Tau217, beta-amyloid 1-42/1-40 ratio, NF-L, GFAP

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Description

SAMPLE TYPE: BLOOD

RESULTS: 21 DAYS

Results delivered from sample reception

Extended Alzheimer Profile is a panel of plasma biomarkers aimed at supporting the diagnosis of Alzheimer’s disease and other neurodegenerative processes. It includes ß-amyloid and phosphorylated tau (p-tau217) as specific markers of amyloid and tau pathology, along with GFAP and neurofilament light (Nf-L) as indicators of astroglial activation and neuroaxonal damage. It contributes to early diagnosis and differential diagnosis of neurodegenerative dementias.

  • Mild cognitive impairment and Alzheimer’s disease
  • Family history/background
  • Specialized preventive assessment
  • Evaluation before anti-amyloid therapies
  • Nonspecific neurological symptoms
  • Suspected unclassified neurodegenerative disease
  • pTau217: protein linked to typical Alzheimer’s changes.
  • Beta-Amyloid 1-42/1-40 ratio: indirect signal of amyloid deposition in the brain, which usually appears years earlier.
  • GFAP: marks the reaction of brain support cells (glia), useful for detecting early changes.
  • NF-L: indicates nerve fiber damage; helps estimate intensity/progression.

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