The GNT. Celiac Disease (Gluten Intolerance) analyzes the genetic variants associated with celiac disease, an autoimmune pathology that causes permanent gluten intolerance. This disease has a significant hereditary component (between 7.5% and 15%), and its genetic diagnosis allows the identification of predisposition even before the onset of symptoms. The study focuses on the alleles of the HLA-DQA1 and HLA-DQB1 genes, fundamental genetic markers for determining susceptibility to celiac disease. A positive result indicates a genetic predisposition, while the absence of these risk alleles rules out the probability of developing it by 95%.
Its objective is to determine the genetic predisposition to celiac disease and differentiate it from non-celiac gluten sensitivity, facilitating a more precise diagnosis and appropriate nutritional intervention.