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Description
SAMPLE TYPE: BLOOD
Requires venous blood draw.
RESULTS: 20 DAYS
Results delivered from sample reception
The GNT. Metabolizer DETOX analyzes genetic variants involved in phases I and II of hepatic detoxification, as well as in oxidative stress and transporters. It helps you understand how you metabolize medicines and environmental toxins, and guides personalized recommendations to reduce adverse effects and optimize the elimination of compounds.
Its aim is to identify genetic predispositions that affect the biotransformation (activation/inactivation) and elimination of xenobiotics and endogenous metabolites, supporting clinical and lifestyle decisions.
This test requires a medical prescription. The requesting healthcare professional must ensure that the patient receives appropriate information and genetic counselling, as well as correct clinical interpretation of the results.
- Identify sensitivity to medications and explain unusual side effects.
- Optimize detoxification in chronic exposure to environmental or occupational toxins.
- Support for diagnosis in nonspecific chronic pathologies where biotransformation dysfunction is suspected.
- Personalize lifestyle habits and supplementation according to the genetic profile.
- Integration into prevention and personalized health strategies together with biomarkers and clinical history.
- Cytochrome p450 and related (Phase I) → CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4, CYP3A5, CYP3A7, CYP4B1, CYP4F2, TBXAS1, PTGIS, CYP19A1, FMO1, POR
- Methylation (Phase II) → COMT, MTHFR, MTR, MTRR
- Acetylation (Phase II) → NAT1, NAT2
- Glucuronidation (Phase II) → UGT1A1, UGT1A3, UGT1A4, UGT1A7, UGT1A8, UGT1A9, UGT1A10, UGT2B7, UGT2B15, UGT2B17
- Sulfation (Phase II) → SULT1A1, SULT1A2, SULT1A4, SULT1E1
- Glutathione→ GSTM1, GSTM2, GSTM3, GSTM4, GSTP1, GSTT1, GSTA1
- Oxidative stress → CAT, SOD1, SOD2, SOD3, OGG1, CDA, DPYD, NQO1
- Transporters → CFTR, SLC15A2, SLCO1B1, SLCO2B1, MTRNR1, ABCB1, ABCC2
For more information, contact the Teletest administration department at 932 12 33 45 or through the following form
