suPAR (soluble urokinase plasminogen activator receptor) is a biomarker related to chronic activation of the innate immune system, systemic inflammation, and long-term biological risk. It is considered a global marker of sustained inflammatory burden, especially useful in contexts where classic markers do not fully reflect the patient’s clinical situation.

Associated Processes:

• Reflects chronic activation of the innate immune system
• Allows assessment of low and high-grade systemic inflammation
• Associated with endothelial damage and incipient organ dysfunction
• Provides information on sustained inflammatory burden over time
• Can aid in risk stratification for complex patients